Intravenous Immunoglobulin (IVIg): Uses, Mechanism, and Clinical Importance
Intravenous Immunoglobulin (IVIg) is a medical therapy made from pooled antibodies collected from healthy human donors. These antibodies, mainly immunoglobulin G (IgG), are administered directly into the bloodstream to help support or regulate the immune system. IVIg is widely used in the treatment of various immune-related and inflammatory conditions, particularly when the body’s immune system is either overactive or deficient.
The primary function of IVIg is to provide passive immunity and modulate immune responses. It works in multiple ways, including neutralizing harmful antibodies, blocking inflammatory pathways, and improving immune regulation. Because of its broad mechanism of action, IVIg is used in several clinical settings where immune imbalance plays a central role.
One of the key applications of IVIg is in primary immunodeficiency disorders. Patients with these conditions have weakened immune systems and are prone to frequent infections. IVIg helps by supplying the…